If you're taking a conventional lipoic acid pill, then you need to know that the healthpromoting, anti-aging benefits associated with this nutrient are only being delivered by half of your supplement. The other half is worse than useless: it actually antagonizes the effects of the good half of the supplement. Many molecules used by the body have a specific "handedness" (chirality) and in some cases, synthetic versions of these molecules have a different "handedness" than the natural molecule. You're probably familiar with some examples of this phenomenon, such as natural d- vs. synthetic dl-alpha-tocopherol or natural cis- vs. unnatural trans-fatty acids. Some of these artificial molecules are merely less potent than the natural forms, such as in the case of dl-alpha-tocopherol but others are actually harmful - for example, trans-fatty acids.
R (+) Lipoic acid is a powerful and versatile antioxidant known for its ability to protect the brain and nerve cells from free radicals and toxins. Lipoic acid has also been used to support healthy blood sugar metabolism.
A study in a short-lived strain of mouse demonstrated that R (+) lipoic acid can dramatically increase its lifespan. Neither S (-) lipoic acid, nor the racemate (blend of R(+) and S(-)), had any significant effect.
It is important to note that unless specified, "lipoic acid" supplements are a 50/50 mixture of the natural R(+) lipoic acid, and the synthetic S (-) lipoic acid. These mixtures are called "racemates." In some cases, S (-) lipoic acid - or the racemate - is simply less effective than R (+) lipoic acid. But in other cases, the S (-) form actually acts in opposition to the activity of R (+) lipoic acid. Common "lipoic acid" supplements are thus like a house at war with itself. The S (-) form should be removed from supplements in favor of pure R (+) lipoic acid as found in AOR's R(+)-Lipoic Acid.
- 90 Vegi-Caps
- Serving Size: 1 Capsule
- R(+)-lipoic acid 150 mg
- Biotin 100 mcg
Adult Dosage: Take one capsule three times daily, or as directed by a qualified health care practitioner.
WARNINGS AND PRECAUTIONS: