Berberine is a naturally occurring constituent of herbs such as goldenseal, Oregon grape, and barberry. Clinical studies have demonstrated that berberine helps to support already normal glucose and lipid metabolism.* It can also promote normal insulin sensitivity and overall cardiovascular health.* In addition, berberine supports a healthy, balanced immune response.* Since 2000, the NOW brand has been supporting Canadians with a mission to provide products that empower people to lead healthier lives. 70% of the NOW products in Canada are made or packaged in Guelph, Ontario, employing hundreds of Canadians from coast to coast. NOW performs 31,000 quality tests every month to ensure you get the highest quality supplements at the best price possible. Our promise - what is on the label, is precisely what is in the bottle.