Lipoic acid (LA), also referred to as alpha-lipoic acid (ALA), is a naturally occurring and necessary biological factor. Although initially classified as a vitamin, LA is not a true vitamin because it can be synthesized in the body. It is a vitamin-like substance with functions similar to the B vitamins. There are two isomers for LA, designated R (R-LA) and S (S-LA), which are mirror images of each other chemically. R-LA is the preferred form, as it is naturally synthesized in the body and more efficiently absorbed, requiring lower doses and yielding higher concentrations than S-LA. R-LA is the biologically active form of lipoic acid and participates as an essential cofactor in biological processes.
LA is one of the most potent and diverse naturally occurring antioxidants. It has several unique abilities: the ability to work as an antioxidant in both water- and lipid-soluble parts of the cell and cell membrane; the ability to regenerate other antioxidants; and the ability to remain active once it neutralizes free radicals. LA has clearly earned its title of being the universal, super antioxidant. LA has long been known to be useful in promoting health and managing chronic diseases, including nervous system disorders and diabetes. It is also becoming known for its ability to boost metabolism, aid in weight loss, and protect against the effects of aging.
